When implementing Microsoft® Windows® Script host, you can safely assume that a scripting engine only calls the IActiveScriptSite interface in the context of the base thread as long as the host does the following:
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Chooses a base thread (generally the thread that contains the message loop).
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Instantiates the scripting engine in the base thread.
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Calls scripting engine methods only from the base thread, except where specifically allowed, as in the cases of IActiveScript::InterruptScriptThread and IActiveScript::Clone.
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Calls the scripting engine's dispatch object only from the base thread.
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Ensures that the message loop runs in the base thread if a window handle is provided.
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Ensures that objects in the host's object model only source events in the base thread.
These rules are automatically followed by all single-threaded hosts. The restricted model described above is intentionally loose enough to allow a host to abort a stuck script by calling IActiveScript::InterruptScriptThread from another thread (initiated by a CTRL+BREAK handler or the like), or to duplicate a script in a new thread using IActiveScript::Clone.
Remarks
None of these restrictions apply to a host that chooses to implement a free-threaded IActiveScriptSite interface and a free-threaded object model. Such a host can use the IActiveScript interface from any thread, without restriction.